tecovirimat will enhance the stage or result of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Observe. Tecovirimat is usually a weak inhibitor of CYP2C8 and CYP2C19. Observe for adverse outcomes if coadministered with sensitive substrates of those enzymes.enasidenib will raise the amount or influence of diazepam by impacting